Bone Drugs - Building or Breaking Bones?

When a patient is diagnosed with osteopenia or osteoporosis, a condition of thinning bone density, they are often prescribed a bisphosphonate drug. These drugs are designed to prevent further loss of bone density. Unfortunately, their method of action prevents bone rebuilding, in the hopes of maintaining bone integrity.  Normally when bones suffer wear and tear, your body would naturally break down the old or damaged bone and replace it with new bone materials to make it as strong or dense as before. Bone drugs, on the other hand, ensure that the old bone doesn’t undergo this remodeling, keeping old bone around. On a bone density or DEXA (x-ray) scan, this bone looks as if it is denser. However, the old bone becomes more brittle and actually increases the risk of fracture.
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