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Posted by Margy Squires on 4/1/2025 to
Fibromyalgia
If you have fibromyalgia (FM), you are well aware of the energy crunch affecting your everyday activities. Do I have enough energy to do this if I do that? Coenzyme Q10 (CoQ10) helps power energy in the cells so it is a must for those with FM. But do you know the rest of the story about CoQ10 and this painful disorder? CoQ10 appears to be low in most disorders, including fibromyalgia and some 900 different autoimmune disorders, which affects body tissues and function. One particularly vulnerable area is the mitochondria, the life spark of cells. Thus, a dysfunction of the mitochondria impacts overall health but also the severity of any disease. Low CoQ10 levels can allow oxidative stress which provokes inflammation that creates more oxidative stress and more cell damage.
An autoimmune disorder is defined as one in which the body's immune system attacks healthy cells and tissues. The immune system is meant to protect your cells against viruses and other harmful invaders. It does this by making specific weapons called antibodies to target and destroy the "enemy". When the immune system gets 'confused", it attacks you instead. Doctors can check for those targeted antibodies with blood tests. For instance, if you have thyroid antibodies, it may indicate Hashimoto's thyroid and a positive rheumatoid factor may indicate rheumatoid arthritis.
There is no test evidence to prove fibromyalgia is an autoimmune disorder.
However, fibromyalgia has a mitochondrial dysfunction. Fibromyalgia is classified as a neuromuscular disease, a syndrome of amplified pain that involves the nervous system and causes a cascade of symptoms in addition to pain. CoQ10 levels are low in this disorder, too.
There's more.
A 2024 review of CoQ10 in autoimmune disorders found most have low levels. Although not classified autoimmune, FM is included in the review under the neuromuscular category. The researchers go on to state that more than 200 Medline studies in which various diseases were given CoQ10 (up to 3000 mg a day for more than 5 years) showed no adverse events. CoQ10 supplementation could also reduce the need for other immune suppressing prescriptions. Could the low CoQ10 levels contribute to disease severity and progression? The study authors say yes. Studies by Dr. M. Cordero have shown supplementing CoQ10 in fibromyalgia patients improves FM symptoms, offering less pain and fibre-fog and more energy. Dr. Cordero and colleagues also found CoQ10 reduced inflammasomes and thus, inflammation.
In another 2024 study, doctors Katz and Leavitt explain that part of the pain in fibro could be from the muscles and not solely from the nervous system. They found pressure "inside" FM muscles was three times higher than normal and the degree of pressure correlated to the patient's pain level. One of the suggested treatments to increase oxygen to painful muscles? A combination of CoQ10 and magnesium.
CoQ10 is a nutrient that plays a key role in mitochondrial function. As such, CoQ10 helps energy production for cell life but also offers protection as an antioxidant against free radicals that cause oxidative stress and cell damage. CoQ10 further quenches harmful inflammatory cytokines which perpetuate the damaging cycle. CoQ10 has a strong safety record as a supplement, too, so it could be added to most treatment protocols.
Want to try CoQ10 for yourself?
TyH offers CoQ10 Bio-Blends™ which combine CoQ10 with other helpful nutrients that support its bioavailability and offer additional benefits. For instance, David's Fibro-Q10™ is specifically in a 100 mg soft gel dose and quantity to match Dr. Cordero's research dose for fibromyalgia. Another is CoQ10 with Omega-3 and lecithin, two nutrients known as "brain nutrients". Both Omega-3 fish oil and lecithin are fat soluble like CoQ10 so they support CoQ10 stability and absorption.
It makes sense, then, to add CoQ10's healthy boost to your energy for fibromyalgia and any autoimmune disorder. Don't forget to help yourself to the high absorption magnesium of Fibro-Care™ too to further help other fibro symptoms and overall health, too!
RESOURCES
- Cordero M, et al. Mitochondrial dysfunction fibromyalgia (and its implications in the pathogenesis). Med Clin (Barc) 2011. Mar 12; 136 (6);252-6.
- Cordero M, et al. Can coenzyme Q10 improve clinical and molecular parameters in fibromyalgia? Antioxidant Redox Signal 2013; October 20: 19(12):1356-61.
- Cordero M, et al. NLRP3 inflammasomes activated in fibromyalgia: the effect of coenzyme Q10.Antioxidant Redox Signal 2014. Mar 10:20(8):169-80.
- Mantle D, Hargreaves IP. Coenzyme Q10 and Autoimmune Disorders: An Overview. Int J Mol Sci 2024. Apr 22:25(8):4526.
- Katz RS, et al. Muscle Pressure Correlates with Pain Levels in Fibromyalgia. J Clin Rheum 2024. Mar 1:30(2):79-83.
©TyH Publications (M. Squires). For informational purposes only.